Clinical approach of Lajjalu in the treatment of Uterine Prolapse
Chemical Approach of Lajjalu (Mimosa Pudica)

ABSTRACT:

Mimosa Pudica is the herb that shows sensation to touch. There are various theories given on this activity like potassium migrates from the motor cell to intercellular spaces upon stimulation of Mimosa. Researches suggested that potassium may be on the osmotic agent; which could account for the pulvinar cell turgor decrease during the seismonaste reaction. It is found that efflux of potassium from pulvinar cells of Mimosa increases. Substantially during the seismonastic response by increasing potassium concentrations in the external solution a decrease in potential was reported. The chemical sensitivity is also reported. It is also called as Nictivastic Movement(Opening and closing) of leaves is a circandian phenomenon and even when kept continuously in light or darkness.

If State or Central Govt Ayush Departments take initiative in arranging camps in Dist Hospitals to treat POP cases according to Ayurveda, will be benefit for the poor and to system of Ayurveda to its popularity at the global level.

Introduction:

Mimosa Pudica is derived from the word Mimic means to allude, to sensitivity of leaves and Pudica means bashfall receiving or shrinking. Mimosa mimics the animal sensitivity i.e. sensitivity to light time of the day; gravity or like Sundew drosera which react to the contact of insect. Some Mimosa is known as sensitive plant; Humble plant; Shame plant; Sleeping grass; touch menos, Lajjalu in Ayurveda, Namaskari in Sanskrit.

Practical and Clinical approach of Mimosa Pudica in Uterine prolapse:



Since 50 years of my Medical practice I have treated number of cases uterine prolapse and POP cases using Mimosa Pudica. Mimosa Pudica will help in uterine prolapse, menorrhagia and Dysfunctional bleeding and pelvic or prolapse in complications because of its medicinal value. The roots and leaves are commonly used(whole plant). The roots are bitter, astringent,aerid,colling vulnerary, allexipharmic, resolvent. Diuretic autospasmatic, euretic, constipating, and Febrigne. They are useful in vitiated conditions of Pilta, Leucoderma, Vaginopathy, Metropathy, Ulcers, Dysentry, Inflammations, burning sensations, Heamorrids, Fistula Scrofula, Conjuctivitis, Cuts and wounds and for Vasicle Caluculi and Externally for Oedema, Rheumatism, Myalgia and Tumors of the Uterus.

Literature Survey on Mimosa Pudica suggests various therapeutic use of plant reported such as Urolithasis, ovulation vitrocidal, antidepressant, estrogenic and antiestrogenic activation, Antiimplantation and antiestrogenic activity, effects on Ostrotis cycle and ovulation, Hyperglycemic, Anticonvulsant activity, hyaluromidase and isolated from Mimosa Pudica were isolation of tubulin, isolation of Tubulin, isolation of C-glycosyl flavours phenolic ketone a noval buffudinolide analysis of 27 aromatic amino acids and chemical constituents of C-glycosyl flavours.

Causes for this uterine prolapse described:

General etiological factors of gynecological disorders i.e. mithyacara, produsta-artava and bija-dosa as causation of utero-vaginal displacements can be explained in following way-
a) Mithyacara-

This heading includes abnormality of diet and mode of life both. Abnormal diet can cause loss of muscular tissue and tone by influencing general nutrition or health. General weakness is considered as a predisposing factor for utero-vaginal displacements.

Coitus with a women sleeping in abnormal posture after surfeit( cause of antarmukhi gynecological disorder) or over uneven bed ( cause of mahayoni), excessive coitus and improper management during labours etc. mode of life may influence may reproductive organs thus the aggravated dosa may settle there and cause utero-vaginal displacement.

b) Abnormalities of artava-

In this context artava refers to ovarian hormones. Marked estrogen deficiency specially after menopause is considered as a cause of loss of tone of supporting ligaments or musculature, which results in utero-vaginal prolapse.

c) Abnormalities of bija-

This heading refers to all congenital laxity of supporting ligaments of uterus is one of the most important cause of uterine prolapse.

Vayu aggravated due to above causes withholding kapha, influences mamsa, dhatu of reproductive system, which are a;ready made vulnerable due to excess coitus etc. and settles there, then pushes downwards or displaces uterus and/or vaginal canal due to laxity of their supporting ligaments or musculature caused by abnormality of artava or bija or any other cause.

Laxana ( Clinical Feauters)-

Displacement of uterus and/or vaginal canal is the only symptom. Following gynecological disorders are characterized with the displacement of uterus and/or vaginal canal. Since the detailed description of all these entities is already given in preceding pages, hence, here, these are described in short.

a) Vaginal prolapse-

Phalini gynecological disorder-
In this disease anterior and/or posterior vaginal walls are prolapsed, its is a description of cyctocele and/or rectocele.

Vatiki gynecological disorder-
Vagbhata has included displacement of yoni in the clinical features of this disease, which appears to be description of laxity of perineum.

b) Displacement of uterus-

1. This entity is characterized with down-wards displacement of uterus after irritation and difficult labour. This resembles first or second degree uterine prolapse.

Classification (of Staging)

Prolapse is staged according to the P.O.P Quantification(P.O.P) system. This is complicated system and subsequently most people use a summarised version namely.

Stage 1: Prolapse into vagina but more than 1 cm above Hymenal remnants

Stage 2: 1 cm above and 1 cm below the Hymenal remarks.

Stage 3: More than 1 cm below the Hymen to about 7 cm below it.

Stage 4: Complete eversion or more than 7 cm below the Hymen.

In Ayurvedic classics utovaginal displacement is described under twenty etiopathogenical disorders. Thus while considering the etiopathogenesis, general etiopathogenesis of gynocological disorders as well as specific etiopathogenesis of gynocological disorders characterised with utrovaginal displacements hold to be consideration.

Laxity of vaginal Musculature and Fibromusculature supporting the uterus and to certain extent vagina is the main cause of displacement of vagina and/or uterus. In otherwards utrovaginal displacement occurs due to abnormality or Kshaya(loss) of mamsa dhatu of these structures. Mamsa dhatu consists mainly of Prithvi Mahabhuta which is predominant in Kapha dosa also. Strength and stability of body parts is mainly accomplished by kapha dosa. For displacement of any body part from its original place, abnormality of vayu is essential. In other words utrovaginal displacement is caused due to vitiation of vayu and kapha both dosas.

Gurbhasaya Bhramsa: Displacement of uterus. This entity is characterised with downward displacement of uterus after irritation and difficult labour. This resembles 1st or 2nd degree uterine prolapse.
Mahayoni gynecological disorder: Firmness and dilation of orifice of uterus(cirvix) and vagina along with muscular protuberance are the clinical feature of this disease. This condition simulates third degree uterine prolapse or procedentia(IV th degree)
Antarmukhi gynocological disorder: In this disease the onfice of yoni(cervix) is crooked and Dysparennia and backache etc. are the cardinal symptoms. This refers to Anterio or retro displacement specially Retroversion and retroflexion of uterus.
Prolapse of uterus and vaginal canal bothtogether. It is called cystocele and/or rectocele. Among these,
1.It is Mahayoni which I have described earlier.

These type of Antarmukti Gynecological disorder may also be successfully treated with Lajjalu treatment according to Ayurveda. Size of the uterus and size of the fibroid also reduced with this treatment. For example, readings noted here.

As of 06/01/2010,

Uterus=(retroverted and retroflexed) is bulky and shows right fundul sub-mucous fibroid 4.3*3.9*3.2 and endometrial cavity is distorted thickness 17mm.

And on 31/05/2010,

Hyperechoic Endometrium is seen 10.7*8.2*5.2 cms not retroverted it measures

7.8*5.6*4.0mm sized fibroid 3.1*2.9mm is noted in the turdus and endometrial thickness is 7mm.

Prevention of P.O.P:

Little attention is paid to the prevention of P.O.P probably because P.O.P occurs many years after the primary incident important factors however are following.

Good obstetrical practice mainly the prevention of prolonged labour(especially prolonged 2nd stage of labour)
Prevention of Obesity.
Healthy lifestyle including exercise and prevention of constipation.
The prevention of Hysterectomy if possible.
Discussion:

Common indication for Hysterectomy are uterine prolapse 51% and Dysfunctional uterine bleeding 34.9% i.e. those two indications can be easily treated with Ayurvedic line of treatment with Lajjalu by which the operation Hysterectomy can be easily avoided and accidental opening bladder while doing plain Vaginal Hysterectomy may happen and Myocardial inforaction after operation within 48hrs may happen can easily be controlled by giving Ayurvedic Live of Medical Treatment in prolapse. Other interesting complications like deep vein thrombosis in femoral artery and psychosis like complications also after two weeks after operation also will not be there. As such, Ayurvedic line of Treatment is more suitable than going to Hysterectomy.

Answered by supercops at Nov 28, 2010 06:07 AM

Clinical approach of Lajjalu in the treatment of Uterine Prolapse
Chemical Approach of Lajjalu (Mimosa Pudica)

ABSTRACT:

Mimosa Pudica is the herb that shows sensation to touch. There are various theories given on this activity like potassium migrates from the motor cell to intercellular spaces upon stimulation of Mimosa. Researches suggested that potassium may be on the osmotic agent; which could account for the pulvinar cell turgor decrease during the seismonaste reaction. It is found that efflux of potassium from pulvinar cells of Mimosa increases. Substantially during the seismonastic response by increasing potassium concentrations in the external solution a decrease in potential was reported. The chemical sensitivity is also reported. It is also called as Nictivastic Movement(Opening and closing) of leaves is a circandian phenomenon and even when kept continuously in light or darkness.

If State or Central Govt Ayush Departments take initiative in arranging camps in Dist Hospitals to treat POP cases according to Ayurveda, will be benefit for the poor and to system of Ayurveda to its popularity at the global level.

Introduction:

Mimosa Pudica is derived from the word Mimic means to allude, to sensitivity of leaves and Pudica means bashfall receiving or shrinking. Mimosa mimics the animal sensitivity i.e. sensitivity to light time of the day; gravity or like Sundew drosera which react to the contact of insect. Some Mimosa is known as sensitive plant; Humble plant; Shame plant; Sleeping grass; touch menos, Lajjalu in Ayurveda, Namaskari in Sanskrit.

Practical and Clinical approach of Mimosa Pudica in Uterine prolapse:



Since 50 years of my Medical practice I have treated number of cases uterine prolapse and POP cases using Mimosa Pudica. Mimosa Pudica will help in uterine prolapse, menorrhagia and Dysfunctional bleeding and pelvic or prolapse in complications because of its medicinal value. The roots and leaves are commonly used(whole plant). The roots are bitter, astringent,aerid,colling vulnerary, allexipharmic, resolvent. Diuretic autospasmatic, euretic, constipating, and Febrigne. They are useful in vitiated conditions of Pilta, Leucoderma, Vaginopathy, Metropathy, Ulcers, Dysentry, Inflammations, burning sensations, Heamorrids, Fistula Scrofula, Conjuctivitis, Cuts and wounds and for Vasicle Caluculi and Externally for Oedema, Rheumatism, Myalgia and Tumors of the Uterus.

Literature Survey on Mimosa Pudica suggests various therapeutic use of plant reported such as Urolithasis, ovulation vitrocidal, antidepressant, estrogenic and antiestrogenic activation, Antiimplantation and antiestrogenic activity, effects on Ostrotis cycle and ovulation, Hyperglycemic, Anticonvulsant activity, hyaluromidase and isolated from Mimosa Pudica were isolation of tubulin, isolation of Tubulin, isolation of C-glycosyl flavours phenolic ketone a noval buffudinolide analysis of 27 aromatic amino acids and chemical constituents of C-glycosyl flavours.

Causes for this uterine prolapse described:

General etiological factors of gynecological disorders i.e. mithyacara, produsta-artava and bija-dosa as causation of utero-vaginal displacements can be explained in following way-
a) Mithyacara-

This heading includes abnormality of diet and mode of life both. Abnormal diet can cause loss of muscular tissue and tone by influencing general nutrition or health. General weakness is considered as a predisposing factor for utero-vaginal displacements.

Coitus with a women sleeping in abnormal posture after surfeit( cause of antarmukhi gynecological disorder) or over uneven bed ( cause of mahayoni), excessive coitus and improper management during labours etc. mode of life may influence may reproductive organs thus the aggravated dosa may settle there and cause utero-vaginal displacement.

b) Abnormalities of artava-

In this context artava refers to ovarian hormones. Marked estrogen deficiency specially after menopause is considered as a cause of loss of tone of supporting ligaments or musculature, which results in utero-vaginal prolapse.

c) Abnormalities of bija-

This heading refers to all congenital laxity of supporting ligaments of uterus is one of the most important cause of uterine prolapse.

Vayu aggravated due to above causes withholding kapha, influences mamsa, dhatu of reproductive system, which are a;ready made vulnerable due to excess coitus etc. and settles there, then pushes downwards or displaces uterus and/or vaginal canal due to laxity of their supporting ligaments or musculature caused by abnormality of artava or bija or any other cause.

Laxana ( Clinical Feauters)-

Displacement of uterus and/or vaginal canal is the only symptom. Following gynecological disorders are characterized with the displacement of uterus and/or vaginal canal. Since the detailed description of all these entities is already given in preceding pages, hence, here, these are described in short.

a) Vaginal prolapse-

Phalini gynecological disorder-
In this disease anterior and/or posterior vaginal walls are prolapsed, its is a description of cyctocele and/or rectocele.

Vatiki gynecological disorder-
Vagbhata has included displacement of yoni in the clinical features of this disease, which appears to be description of laxity of perineum.

b) Displacement of uterus-

1. This entity is characterized with down-wards displacement of uterus after irritation and difficult labour. This resembles first or second degree uterine prolapse.

Classification (of Staging)

Prolapse is staged according to the P.O.P Quantification(P.O.P) system. This is complicated system and subsequently most people use a summarised version namely.

Stage 1: Prolapse into vagina but more than 1 cm above Hymenal remnants

Stage 2: 1 cm above and 1 cm below the Hymenal remarks.

Stage 3: More than 1 cm below the Hymen to about 7 cm below it.

Stage 4: Complete eversion or more than 7 cm below the Hymen.

In Ayurvedic classics utovaginal displacement is described under twenty etiopathogenical disorders. Thus while considering the etiopathogenesis, general etiopathogenesis of gynocological disorders as well as specific etiopathogenesis of gynocological disorders characterised with utrovaginal displacements hold to be consideration.

Laxity of vaginal Musculature and Fibromusculature supporting the uterus and to certain extent vagina is the main cause of displacement of vagina and/or uterus. In otherwards utrovaginal displacement occurs due to abnormality or Kshaya(loss) of mamsa dhatu of these structures. Mamsa dhatu consists mainly of Prithvi Mahabhuta which is predominant in Kapha dosa also. Strength and stability of body parts is mainly accomplished by kapha dosa. For displacement of any body part from its original place, abnormality of vayu is essential. In other words utrovaginal displacement is caused due to vitiation of vayu and kapha both dosas.

Gurbhasaya Bhramsa: Displacement of uterus. This entity is characterised with downward displacement of uterus after irritation and difficult labour. This resembles 1st or 2nd degree uterine prolapse.
Mahayoni gynecological disorder: Firmness and dilation of orifice of uterus(cirvix) and vagina along with muscular protuberance are the clinical feature of this disease. This condition simulates third degree uterine prolapse or procedentia(IV th degree)
Antarmukhi gynocological disorder: In this disease the onfice of yoni(cervix) is crooked and Dysparennia and backache etc. are the cardinal symptoms. This refers to Anterio or retro displacement specially Retroversion and retroflexion of uterus.
Prolapse of uterus and vaginal canal bothtogether. It is called cystocele and/or rectocele. Among these,
1.It is Mahayoni which I have described earlier.

These type of Antarmukti Gynecological disorder may also be successfully treated with Lajjalu treatment according to Ayurveda. Size of the uterus and size of the fibroid also reduced with this treatment. For example, readings noted here.

As of 06/01/2010,

Uterus=(retroverted and retroflexed) is bulky and shows right fundul sub-mucous fibroid 4.3*3.9*3.2 and endometrial cavity is distorted thickness 17mm.

And on 31/05/2010,

Hyperechoic Endometrium is seen 10.7*8.2*5.2 cms not retroverted it measures

7.8*5.6*4.0mm sized fibroid 3.1*2.9mm is noted in the turdus and endometrial thickness is 7mm.

Prevention of P.O.P:

Little attention is paid to the prevention of P.O.P probably because P.O.P occurs many years after the primary incident important factors however are following.

Good obstetrical practice mainly the prevention of prolonged labour(especially prolonged 2nd stage of labour)
Prevention of Obesity.
Healthy lifestyle including exercise and prevention of constipation.
The prevention of Hysterectomy if possible.
Discussion:

Common indication for Hysterectomy are uterine prolapse 51% and Dysfunctional uterine bleeding 34.9% i.e. those two indications can be easily treated with Ayurvedic line of treatment with Lajjalu by which the operation Hysterectomy can be easily avoided and accidental opening bladder while doing plain Vaginal Hysterectomy may happen and Myocardial inforaction after operation within 48hrs may happen can easily be controlled by giving Ayurvedic Live of Medical Treatment in prolapse. Other interesting complications like deep vein thrombosis in femoral artery and psychosis like complications also after two weeks after operation also will not be there. As such, Ayurvedic line of Treatment is more suitable than going to Hysterectomy.

Answered by supercops at Nov 28, 2010 06:07 AM